Tests

PCI offers the following specialist assays including interpretation and reporting with MDT support if required:

Breast

PD-L1 IHC for TNBC
Her-2 IHC (alone or inclusive of reflex DDISH)
Her-2 DDISH
ER & PR IHC (alone or in combination)
ER, PR & Her-2 IHC (alone or inclusive of reflex DDISH)

Non small cell lung cancer

ALK IHC
PD-L1 IHC
ROS-1 IHC
BRAFV600E IHC
EGFR PCR
BRAF PCR

All the above can be packaged together for a 48h TAT
FISH for ALK or ROS-1 has additional cost

Colorectal cancer

KRAS PCR
BRAF PCR
NRAS PCR
MMR IHC (alone or inclusive of BRAFV600E IHC)
BRAFV600E IHC
Her-2 IHC (and DDISH)
PTEN (IHC)

All the above can be packaged together for a 48h TAT

Melanoma

BRAFV600E IHC
BRAF PCR
NRAS PCR
PD-L1 IHC
BAP-1 IHC
PRAME IHC

Other

PD-L1 IHC for mUC or other indications
MMR IHC (alone or inclusive of BRAFV600E IHC)
BRAFV600E IHC for thyroid or other cancer sites
p16INK4A IHC
Basal cell cocktail (34BE12, p63, P504s) multiplex IHC for prostate biopsies
ERG/PTEN multiplex IHC for prostate cancer
p16INK4A/Ki-67 multiplex IHC for cervical biopsies

Guide Prices per Test

ER, PR, Her2	£100
PD-L1, EGFR, ALK-1, BRAF, ROS-1	£600
MSH-6, MSH-2, MLH-1, PMS-2, BRAF	£180
KRAS, BRAF, NRAS, MMR	£460
Rapid BRAF for melanoma (if negative, it requires PCR for BRAF and NRAS)	£90 £170
PD-L1 SP142 or SP263	£175
IHC	£20-£45
ISH	£170
Multiplex IHC	P.O.A.

Wet tissue to diagnosis:

small biopsies	£70 – £150
large non-cancer	£120 – £250
large cancer	£300 – £500

Reporting only:

small biopsies	£35 – £50
large non-cancer	£60 – £150
large cancer	£120 – £250

Many of these tests have been arranged into commonly used panels with an associated reduction in cost.

PCI welcomes enquiries to discuss your exact requirements using the following contact details:
admin@poundburycancerinstitute.org